TOP研究業績/Publications

主な研究業績 2003年~ / Main Publications from 2003

K. Matsuda, S. Kanaoka, M. Akamatsu and D. B. Sattelle, Diverse actions and target-site selectivity of neonicotinoids: structural insights. Mol. Pharmacol. 76, 1-10 (2009).

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M. Morimoto, C. L. Cantrell, L. Linous-Bailey and S. O. Duke, Phytotoxicity of constituents of glandular trichomes and the leaf surface of camphorweed, Heterotheca subaxillaris. Phytochemistry, 70, 69-74 (2009).

David B. Sattelle, Steven D. Buckingham, Miki Akamatsu, Kazuhiko Matsuda, Ilse S. Pienaar, Andrew K. Jones, Benedict M. Sattelle, Andrew Almond and Charles D. Blundell, Comparative pharmacology and computational modelling yield insights into allosteric modulation of human α7 nicotinic acetylcholine receptors. Biochem. Pharmacol. 78, 836-843 (2009).

Andrew K. Jones, Steven D. Buckingham, Magdalini Papadaki, Maiko Yokota, Benedict M. Sattelle, Kazuhiko Matsuda, and David B. Sattelle, Splice variant- and stage-specific RNA editing of the Drosophila GABA receptor, Rdl, modulate agonist potency. J. Neurosci. 29, 4287-4292 (2009).

Kayoko Toshima, Satoshi Kanaoka, Atsushi Yamada, Kiyoshi Tarumoto, Miki Akamatsu, David B. Sattelle and Kazuhiko Matsuda, Combined roles of loops C and D in the interactions of a neonicotinoid insecticide imidacloprid with the a4b2 nicotinic acetylcholine receptor. Neuropharmacology 56, 264-272 (2009).

Koichi Hirata, Chiharu Ishida, Yoko Eguchi, Kazuki Sakai, Fumiyo Ozoe, Yoshihisa Ozoe and Kazuhiko Matsuda, Role of a serine residue (S278) in the pore-facing region of the housefly L-glutamate-gated chloride channel in determining the sensitivity to noncompetitive antagonists. Insect Mol. Biol. 17, 341-350 (2008).

Lijun Liu, Mohammad Sayed Alam, Koichi Hirata, Kazuhiko Matsuda and Yoshihisa Ozoe, Actions of quinolizidine alkaloids on Periplaneta americana nicotinic acetylcholine receptors. Pest Manag. Sci. 64, 1222-1228 (2008).

Makoto Ihara, Toshihide Okajima, Atsuko Yamashita, Takuma Oda, Koichi Hirata, Hisashi Nishiwaki, Takako Morimoto, Miki Akamatsu, Yuji Ashikawa, Shun’ichi Kuroda, Ryosuke Mega, Seiki Kuramitsu, David B. Sattelle and Kazuhiko Matsuda, Crystal structures of Lymnaea stagnalis AChBP in complex with neonicotinoid insecticides imidacloprid and clothianidin. Invert. Neurosci. 8, 71-81 (2008)

Shiva Amiri, Masaru Shimomura, Ranjit Vijayan, Hisashi Nishiwaki, Miki Akamatsu, Kazuhiko Matsuda, Andrew K. Jones, Mark S.P. Sansom, Philip C. Biggin and David B. Sattelle, A Role for Leu118 of Loop E in Agonist Binding to the a7 Nicotinic Acetylcholine Receptor. Mol. Pharmacol. 73, 1659-1667 (2008).

Kayoko Toshima, Makoto Ihara, Satoshi Kanaoka, Kiyoshi Tarumoto, Atsushi Yamada, David B. Sattelle and Kazuhiko Matsuda, Potentiating and blocking actions of neonicotinoids on the response to acetylcholine of the neuronal a4b2 nicotinic acetylcholine receptor. J. Pestic. Sci. 33, 146-151 (2008)

Hiroshi Okuda, Chihaya Sakuhana, Risa Yamamoto, Yuko Mizukami, Rika Kawai, Yusuke Sumita, Motoki Koga, Mutsunori Shirai, and Kazuhiko Matsuda, Intermediate domain defines broad nucleotide selectivity for protein folding in Chlamydophila GroEL1. J. Biol. Chem. 283, 9300-9307 (2008).

Kenzo Fujimoto, Yoshinaga Yoshimura, Makoto Ihara, Kazuhiko Matsuda, Yuko Takeuchi, Takaaki Aoki and Toru Ide, Cy3-3-Acylcholine: a Fluorescent analogue of acetylcholine for single molecule detection, Bioorg. Med. Chem. Lett. 18, 1106-1109 (2008).

M. Morimoto, H. Fukumoto, T. Nozoe, A. Hagiwara and K. Komai, Synthesis and insect antifeedant activity of aurones against Spodoptera litura larvae. J. Agric. Food Chem. 55, 700-705 (2007).

I. Ohno, K. Hirata, C. Ishida, M. Ihara, K. Matsuda and S. Kagabu, N-(5-methyl-2-oxo-1,3-dioxol-4-yl)methyl derivatives of imidacloprid and 1-chlorothiazolylmethyl-2-nitroimino-imidazolidine. Bioorg. Med. Chem. Lett. 17, 4500-4503 (2007).

M. Ihara, K. Hirata, C. Ishida, S. Kagabu and K. Matsuda, Blocking actions of alkylene-tethered bis-neonicotinoids on nicotinic acetylcholine receptors expressed by terminal abdominal ganglion neurons of Periplaneta americana. Neurosci. Lett. 425, 137-140 (2007).

H. Nishiwaki, K. Nakashima, C. Ishida, T. Kawamura and K. Matsuda, Cloning, functional characterization and mode of action of a novel insecticidal pore-forming toxin, sphaericolysin, produced by a Bacillus sphaericus. Appl. Environ. Microbiol. 73, 3404-3411 (2007).

H. Nishiwaki, K. Ito, M. Shimomura, K. Nakashima and K. Matsuda, Insecticidal bacteria isolated from predatory larvae of the antlion species Myrmeleon bore (Neuropterae: Myrmeleontidae), J. Invert. Pathol. 96, 80-88 (2007).

H. Okuda, C. Sakuhana, R. Yamamoto, R. Kawai, Y. Mizukami and K. Matsuda, Effects of divalent cations on encapsulation and release in the GroEL-assisted folding, BioMetals 20, 903-910 (2007).

M. Morimoto, H. Fukumoto, T. Nozoe, A. Hagiwara and Komai, K. Synthesis and insect antifeedant activity of aurones against Spodoptera litura larvae. J. Agric. Food Chem, 55, 700-705 (2006).



Y. Eguchi, M. Ihara, E. Ochi, Y. Shibata, K. Matsuda, S. Fushiki, H. Sugama, Y. Hamasaki, H. Niwa, M. Wada, F. Ozoe and Y. Ozoe, Functional characterization of Musca glutamate- and GABA-gated chloride channels expressed independently and co-expressed in Xenopusoocytes. Insect Mol. Biol., 15, 773-783 (2006).

M. Shimomura, M.Yokota, M. Ihara, M. Akamatsu, D. B. Sattelle and K. Matsuda, Role in the selectivity of neonicotinoids of insect-specific basic residues in loop D of the nicotinic acetylcholine receptor agonist binding site. Mol. Pharmacol., 70, 1255-1263 (2006).   

M. Morimoto, H. Fukumoto, M. Hiratani, W. Chavasiri and K. Komai, Insect Antifeedants, Pterocarpans and Pterocarpol, in Heartwood of Pterocarpus macrocarpus Kruz. Biosci. Biotechnol. Biochem. 70, 1864-1868 (2006).

M. Ihara, L. A. Brown, C. Ishida, H. Okuda, D. B. Sattelle and K. Matsuda, Actions of imidacloprid, clothianidin and related neonicotinoids on nicotinic acetylcholine receptors of American cockroach neurons and their relationships with insecticidal potency. J. Pestic. Sci. 31, 35 ? 40 (2006).

M. Ihara, C. Ishida, H. Okuda, Y. Ozoe and K. Matsuda, Differential blocking actions of 4’-ethynyl-4-n- propylbicycloorthobenzoate (EBOB) and g-hexachlorocyclohexane on g-aminobutyric acid and glutamic acid-induced responses of American cockroach neurons. Invert. Neurosci. 5, 157 ? 164 (2005).

M. Shimomura, H. Satoh, M. Yokota, M. Ihara, K. Matsuda and D. B. Sattelle, Insect-vertebrate chimeric nicotinic acetylcholine receptors identify a region, loop B to the N-terminus of the Drosophila Da2 subunit, which contributes to neonicotinoid sensitivity. Neurosci. Lett., 385, 168-172 (2005).

K. Matsuda, Y. Kikuta, K. Nakayama, S. Katsuda, A. Hatanaka and K. Komai, Biosynthesis of pyrethrin I in seedlings of Chrysanthemum cinerariaefolium. Phytochemistry, 66, 1529-1535 (2005).

M. Shimomura, K. Matsuda, M. Akamatsu, D. B. Sattelle and K. Komai, Responses to neonicotinoids of chicken a7 nicotinic acetylcholine receptors: Effects of mutations of isoleucine 191 in loop F to aromatic residues. J. Pestic. Sci., 29, 364-368 (2004).

K. Fukuoka, A. Sawabe, T. Sugimoto, M. Koga, H. Okuda, T. Kitayama, M. Shirai, K. Komai, S. Komemushi, and K. Matsuda, Inhibitory actions of several natural products on proliferation of rat vascular smooth muscle cells induced by Hsp60 from Chlamydia pneumoniae J138. J. Agric. Food Chem., 52, 6326-6329 (2004).

M. Morimoto, K. Matsuda, Y. Ohta, T. Ihara and K. Komai, Evaluation of calcium-alginate gel as an artificial diet medium for bioassays on common cutworms. J. Agric. Food Chem., 52, 4737-4739 (2004).



M. Shimomura, M. Yokota, K. Matsuda, D. B. Sattelle and K. Komai, Roles of loop C and the loop B?C interval of the nicotinic receptor a subunit in its selective interactions with imidacloprid in insects. Neurosci. Lett., 363, 195-198 (2004).

M. Ihara, K. Matsuda, M. Shimomura, D. B. Sattelle and K. Komai, Super agonist actions of clothianidin and related compounds on the SADb2 nicotinic acetylcholine receptor expressed in Xenopus laevis oocytes. Biosci. Biotechnol. Biochem., 68, 761-763 (2004).

H. Nishiwaki, K. Ito, K. Otsuki, H. Yamamoto, K. Komai and K. Matsuda, Purification and functional characterization of insecticidal sphingomyelinase C produced by Bacillus cereus. Eur. J. Biochem., 271, 601-606 (2004).

M. Shimomura, M. Yokota, M. Okumura, K. Matsuda, M. Akamatsu, D. B. Sattelle and K. Komai, Combinatorial mutations in loops D and F strongly influence responses of the a7 nicotinic acetylcholine receptor to imidacloprid. Brain Res., 991, 71-77 (2003).

H. Nishiwaki, Y. Nakagawa, M. Kuwamura, K. Sato, M. Akamatsu, K. Matsuda, K. Komai and H. Miyagwa, Correlations of the electrophysiological activity of neonicotinoids with their binding and insecticidal activities. Pest Manag. Sci. 59, 1023-1030 (2003).

M. Ihara, K. Matsuda, M. Otake, M. Kuwamura, M. Shimomura, K. Komai, M. Akamatsu, V. Raymond, D. B. Sattelle, Diverse actions of neonicotinoids on chicken a7, a4b2 and Drosophila-chicken SADb2 and ALSb2 hybrid nicotinic acetylcholine receptors expressed in Xenopus laevis oocytes. Neuropharmacology 45, 133-144 (2003).


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